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Host cells of HIV quicken the release of the virus |
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Written by Dr. H. P. Bustami
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Tuesday, 23 December 2008 |
 HIV-Virus leaving the host cell (3-D-electron-tomographie photograph, courtesy: University hospital of Heidelberg, Germany) Scientists from Germany discovered an unknown mechanism in host cells of the AIDS-Virus. HIV affects cells of the immune system in humans. Viruses transform their hosts for their own purposes and reproduction. Finally they are released from the infected cell and start befalling other immune cells. But how is this achieved by the virus? The latest research results of german scientists from Heidelberg and Munich suggest an active role of the host cell itself!
With hightech-microscopy methods it could be shown that the host cells
"help" releasing the AIDS-Virus at the cell membrane by producing a
certain protein complex, called ESCRT. It helps cut off the connection
between a the "baby-virus" and the cell surface of the host cell.
With a special three dimensional electron microscopy method - called electron tomographie - sensational photographs of AIDS-viruses leaving their host cell were made. In the electron tomographie the slices of cell membranes are shock frozen at - 196
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